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Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro

Small-molecule immunosuppressive drugs (ISD) prevent graft rejection mainly by inhibiting T lymphocytes. Therapeutic immunoglobulins (IVIg) are used for substitution, antibody-mediated rejection (AbMR) and HLA-sensitized recipients by targeting distinct cell types. Since the effect of ISD and IVIg o...

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Detalles Bibliográficos
Autores principales: Pradier, Amandine, Papaserafeim, Maria, Li, Ning, Rietveld, Anke, Kaestel, Charlotte, Gruaz, Lyssia, Vonarburg, Cédric, Spirig, Rolf, Puga Yung, Gisella L., Seebach, Jörg D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445861/
https://www.ncbi.nlm.nih.gov/pubmed/30972058
http://dx.doi.org/10.3389/fimmu.2019.00556