Cargando…

Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro

Small-molecule immunosuppressive drugs (ISD) prevent graft rejection mainly by inhibiting T lymphocytes. Therapeutic immunoglobulins (IVIg) are used for substitution, antibody-mediated rejection (AbMR) and HLA-sensitized recipients by targeting distinct cell types. Since the effect of ISD and IVIg o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pradier, Amandine, Papaserafeim, Maria, Li, Ning, Rietveld, Anke, Kaestel, Charlotte, Gruaz, Lyssia, Vonarburg, Cédric, Spirig, Rolf, Puga Yung, Gisella L., Seebach, Jörg D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445861/ https://www.ncbi.nlm.nih.gov/pubmed/30972058 http://dx.doi.org/10.3389/fimmu.2019.00556

Ejemplares similares

NK Cell Isolation from Liver Biopsies: Phenotypic and Functional Analysis of Low Cell Numbers by Flow Cytometry
por: Li, Ning, et al.
Publicado: (2013)

The Role of NK Cells in Pig-to-Human Xenotransplantation
por: Puga Yung, Gisella, et al.
Publicado: (2017)

Brief Exercise Increases Peripheral Blood NK Cell Counts without Immediate Functional Changes, but Impairs their Responses to ex vivo Stimulation
por: Millard, Anne-Laure, et al.
Publicado: (2013)

Depletion of abundant plasma proteins for extracellular vesicle proteome characterization: benefits and pitfalls
por: Reymond, Sandrine, et al.
Publicado: (2023)

Immunosuppressive Effects of Streptozotocin-Induced Diabetes Result in Absolute Lymphopenia and a Relative Increase of T Regulatory Cells
por: Muller, Yannick D., et al.
Publicado: (2011)

T-bet and Eomesodermin in NK Cell Development, Maturation, and Function
por: Simonetta, Federico, et al.
Publicado: (2016)

Blockade of T Cell Contact-Activation of Human Monocytes by High-Density Lipoproteins Reveals a New Pattern of Cytokine and Inflammatory Genes
por: Gruaz, Lyssia, et al.
Publicado: (2010)

Block-Removed Immunoglobulin Technology to enhance rituximab effector function by counteracting CA125-mediated immunosuppression
por: Grasso, Luigi, et al.
Publicado: (2022)

High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals
por: Scanu, Anna, et al.
Publicado: (2010)

HDL Interfere with the Binding of T Cell Microparticles to Human Monocytes to Inhibit Pro-Inflammatory Cytokine Production
por: Carpintero, Rakel, et al.
Publicado: (2010)

Modulation of T-bet and Eomes during Maturation of Peripheral Blood NK Cells Does Not Depend on Licensing/Educating KIR
por: Pradier, Amandine, et al.
Publicado: (2016)

Epigenetic regulation of NK cell differentiation and effector functions
por: Cichocki, Frank, et al.
Publicado: (2013)

Human NK cells: From development to effector functions
por: Perera Molligoda Arachchige, Arosh Shavinda
Publicado: (2021)

NK cell markers predict the efficacy of IV immunoglobulins in CIDP
por: Mausberg, Anne K., et al.
Publicado: (2020)

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function
por: Stetson, Daniel B., et al.
Publicado: (2003)

Immunosuppression by immunoglobulin deaggregation is not effective in reducing the anti-xenogeneic immunoglobulin response: experimental and clinical studies.
por: Sivolapenko, G. B., et al.
Publicado: (1989)

Functionally Diverse NK-Like T Cells Are Effectors and Predictors of Successful Aging
por: Michel, Joshua J., et al.
Publicado: (2016)

Monomeric Immunoglobulin A from Plasma Inhibits Human Th17 Responses In Vitro Independent of FcαRI and DC-SIGN
por: Saha, Chaitrali, et al.
Publicado: (2017)

Anti-CD154 mAb and Rapamycin Induce T Regulatory Cell Mediated Tolerance in Rat-to-Mouse Islet Transplantation
por: Muller, Yannick D., et al.
Publicado: (2010)

Optimizing NK Cell-Based Immunotherapy in Myeloid Leukemia: Abrogating an Immunosuppressive Microenvironment
por: Kaweme, Natasha Mupeta, et al.
Publicado: (2021)

Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites
por: Hrvat, Antonio, et al.
Publicado: (2023)

IMMUNOSUPPRESSION OF MICE INJECTED WITH HETEROLOGOUS ANTI-IMMUNOGLOBULIN HEAVY CHAIN ANTISERA
por: Manning, Dean D., et al.
Publicado: (1972)

Human pegivirus-1 replication influences NK cell reconstitution after allogeneic haematopoietic stem cell transplantation
por: Pradier, Amandine, et al.
Publicado: (2023)

The Peripheral NK Cell Repertoire after Kidney Transplantation is Modulated by Different Immunosuppressive Drugs
por: Neudoerfl, Christine, et al.
Publicado: (2013)

Priming of NK Cell Anti-Viral Effector Mechanisms by Direct Recognition of Human Cytomegalovirus
por: Muntasell, Aura, et al.
Publicado: (2013)

Intra- and Extracellular Effector Vesicles From Human T And NK Cells: Same-Same, but Different?
por: Lettau, Marcus, et al.
Publicado: (2021)

Cell Type-Specific Cleavage of Nucleocapsid Protein by Effector Caspases during SARS Coronavirus Infection
por: Diemer, Claudia, et al.
Publicado: (2008)

Susceptibility of Human Melanoma Cells to Autologous Natural Killer (NK) Cell Killing: HLA-Related Effector Mechanisms and Role of Unlicensed NK Cells
por: Carrega, Paolo, et al.
Publicado: (2009)

CD56(neg)CD16(+) NK cells are activated mature NK cells with impaired effector function during HIV-1 infection
por: Milush, Jeffrey M, et al.
Publicado: (2013)

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections
por: Jensen, Isaac J., et al.
Publicado: (2018)

From Tumor Immunosuppression to Eradication: Targeting Homing and Activity of Immune Effector Cells to Tumors
por: Draghiciu, Oana, et al.
Publicado: (2011)

Post-Transplant Immunosuppression: Regulation of the Efflux of Allospecific Effector T Cells from Lymphoid Tissues
por: Swan, David J., et al.
Publicado: (2012)

High immunosuppressive burden in advanced hepatocellular carcinoma patients: Can effector functions be restored?
por: Lugade, Amit A, et al.
Publicado: (2013)

Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients
por: De Matteis, Serena, et al.
Publicado: (2018)

NK Cells of Kidney Transplant Recipients Display an Activated Phenotype that Is Influenced by Immunosuppression and Pathological Staging
por: Hoffmann, Ulrike, et al.
Publicado: (2015)

Regulatory NK cells mediated between immunosuppressive monocytes and dysfunctional T cells in chronic HBV infection
por: Li, Haijun, et al.
Publicado: (2018)

BTLA/HVEM Axis Induces NK Cell Immunosuppression and Poor Outcome in Chronic Lymphocytic Leukemia
por: Sordo-Bahamonde, Christian, et al.
Publicado: (2021)

The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions
por: Todros-Dawda, Izabela, et al.
Publicado: (2014)

Pneumococcal polysaccharide vaccination in adults undergoing immunosuppressive treatment for inflammatory diseases – a longitudinal study
por: Fischer, Lara, et al.
Publicado: (2015)

Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies
Publicado: (1987)

Cannot write session to /tmp/vufind_sessions/sess_do6is77aqimscepcj4rti0aapr