Histone Deacetylase Inhibitor Modulates NKG2D Receptor Expression and Memory Phenotype of Human Gamma/Delta T Cells Upon Interaction With Tumor Cells

The functional plasticity and anti-tumor potential of human γδ T cells have been widely studied. However, the epigenetic regulation of γδ T-cell/tumor cell interactions has been poorly investigated. In the present study, we show that treatment with the histone deacetylase inhibitor Valproic acid (VP...

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Detalles Bibliográficos
Autores principales: Bhat, Jaydeep, Dubin, Samuel, Dananberg, Alexandra, Quabius, Elgar Susanne, Fritsch, Juergen, Dowds, C. Marie, Saxena, Ankit, Chitadze, Guranda, Lettau, Marcus, Kabelitz, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445873/
https://www.ncbi.nlm.nih.gov/pubmed/30972064
http://dx.doi.org/10.3389/fimmu.2019.00569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445873/
https://www.ncbi.nlm.nih.gov/pubmed/30972064
http://dx.doi.org/10.3389/fimmu.2019.00569

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