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Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the l-Fucose Metabolism of Gut Bifidobacterium spp. and Lactobacillus spp.

The maternal milk glycobiome is crucial for shaping the gut microbiota of infants. Although high core fucosylation catalyzed by fucosyltransferase 8 (Fut8) is a general feature of human milk glycoproteins, its role in the formation of a healthy microbiota has not been evaluated. In this study, we fo...

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Detalles Bibliográficos
Autores principales: Li, Ming, Bai, Yaqiang, Zhou, Jiaorui, Huang, Wei, Yan, Jingyu, Tao, Jia, Fan, Qingjie, Liu, Yang, Mei, Di, Yan, Qiulong, Yuan, Jieli, Malard, Patrice, Wang, Zhongfu, Gu, Jianguo, Tanigchi, Naoyuki, Li, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445936/
https://www.ncbi.nlm.nih.gov/pubmed/30940702
http://dx.doi.org/10.1128/mBio.00128-19