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Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state credited with over 200,000 life-threatening infections each year. The triazole class of antifungals are clinically essential to the treatment of invasive aspergillosis, both as frontline and as salvage thera...

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Detalles Bibliográficos
Autores principales: Rybak, Jeffrey M., Ge, Wenbo, Wiederhold, Nathan P., Parker, Josie E., Kelly, Steven L., Rogers, P. David, Fortwendel, Jarrod R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445940/
https://www.ncbi.nlm.nih.gov/pubmed/30940706
http://dx.doi.org/10.1128/mBio.00437-19