MicroRNA-134-5p Regulates Media Degeneration through Inhibiting VSMC Phenotypic Switch and Migration in Thoracic Aortic Dissection

Abnormal phenotypic switch, migration, and proliferation of vascular smooth muscle cells (VSMCs) are hallmarks for pathogenesis of thoracic aortic dissection (TAD). In the current study, we identified miR-134-5p as a critical regulator controlling human VSMC phenotypic switch and migration to invest...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Dong, Chang-Qing, Peng, Guang-Yin, Huang, Hao-yue, Yu, Yun-sheng, Ji, Zhen-Chun, Shen, Zhen-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446055/
https://www.ncbi.nlm.nih.gov/pubmed/30951965
http://dx.doi.org/10.1016/j.omtn.2019.02.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446055/
https://www.ncbi.nlm.nih.gov/pubmed/30951965
http://dx.doi.org/10.1016/j.omtn.2019.02.021

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