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Halted Lymphocyte Egress via Efferent Lymph Contributes to Lymph Node Hypertrophy During Hypercholesterolemia

Dyslipidemia is a central component of atherosclerosis and metabolic syndrome linked to chronic inflammation and immune dysfunction. Previously, we showed that hypercholesterolemic apolipoprotein E knock out (apoE(−/−)) mice exhibit systemic effects including skin inflammation and hypertrophic lymph...

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Detalles Bibliográficos
Autores principales: Tay, Meng Hwee Daniel, Lim, Swee Yeng Jason, Leong, Yew Fai Ivan, Thiam, Chung Hwee, Tan, Kar Wai, Torta, Federico Tesio, Narayanaswamy, Pradeep, Wenk, Markus, Angeli, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446103/
https://www.ncbi.nlm.nih.gov/pubmed/30972070
http://dx.doi.org/10.3389/fimmu.2019.00575