TranscriptAchilles: a genome-wide platform to predict isoform biomarkers of gene essentiality in cancer

BACKGROUND: Aberrant alternative splicing plays a key role in cancer development. In recent years, alternative splicing has been used as a prognosis biomarker, a therapy response biomarker, and even as a therapeutic target. Next-generation RNA sequencing has an unprecedented potential to measure the...

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Detalles Bibliográficos
Autores principales: Carazo, Fernando, Campuzano, Lucía, Cendoya, Xabier, Planes, Francisco J, Rubio, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446222/
https://www.ncbi.nlm.nih.gov/pubmed/30942869
http://dx.doi.org/10.1093/gigascience/giz021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446222/
https://www.ncbi.nlm.nih.gov/pubmed/30942869
http://dx.doi.org/10.1093/gigascience/giz021

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