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TranscriptAchilles: a genome-wide platform to predict isoform biomarkers of gene essentiality in cancer
BACKGROUND: Aberrant alternative splicing plays a key role in cancer development. In recent years, alternative splicing has been used as a prognosis biomarker, a therapy response biomarker, and even as a therapeutic target. Next-generation RNA sequencing has an unprecedented potential to measure the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446222/ https://www.ncbi.nlm.nih.gov/pubmed/30942869 http://dx.doi.org/10.1093/gigascience/giz021 |