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Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome

BACKGROUND: The polymeric immunoglobulin receptor (pIgR) maintains the integrity of epithelial barriers by transporting polymeric antibodies and antigens through the epithelial mucosa into the lumen. In this study, we examined the role of pIgR in maintaining gut barrier integrity, which is important...

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Detalles Bibliográficos
Autores principales: Simpfendorfer, Kim R., Wang, Nancy, Tull, Dedreia L., De Souza, David P., Nahid, Amsha, Mu, Andre, Hocking, Dianna M., Pedersen, John S., Wijburg, Odilia L. C., McConville, Malcolm J., Strugnell, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446318/
https://www.ncbi.nlm.nih.gov/pubmed/30943912
http://dx.doi.org/10.1186/s10020-019-0077-2