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Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome
BACKGROUND: The polymeric immunoglobulin receptor (pIgR) maintains the integrity of epithelial barriers by transporting polymeric antibodies and antigens through the epithelial mucosa into the lumen. In this study, we examined the role of pIgR in maintaining gut barrier integrity, which is important...
Autores principales: | Simpfendorfer, Kim R., Wang, Nancy, Tull, Dedreia L., De Souza, David P., Nahid, Amsha, Mu, Andre, Hocking, Dianna M., Pedersen, John S., Wijburg, Odilia L. C., McConville, Malcolm J., Strugnell, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446318/ https://www.ncbi.nlm.nih.gov/pubmed/30943912 http://dx.doi.org/10.1186/s10020-019-0077-2 |
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