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Flagellin attenuates experimental sepsis in a macrophage-dependent manner

BACKGROUND: Sepsis is the leading cause of death among critically ill patients, and no specific therapeutic agent is currently approved for the treatment of sepsis. METHODS: We assessed the effects of flagellin administration on survival, bacterial burden, and tissue injury after sepsis. In addition...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoliang, Yin, Yibing, Yan, Xingxing, Yu, Zebo, Liu, Yi, Cao, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446324/
https://www.ncbi.nlm.nih.gov/pubmed/30944018
http://dx.doi.org/10.1186/s13054-019-2408-7