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An average-case sublinear forward algorithm for the haploid Li and Stephens model
BACKGROUND: Hidden Markov models of haplotype inheritance such as the Li and Stephens model allow for computationally tractable probability calculations using the forward algorithm as long as the representative reference panel used in the model is sufficiently small. Specifically, the monoploid Li a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446408/ https://www.ncbi.nlm.nih.gov/pubmed/30988694 http://dx.doi.org/10.1186/s13015-019-0144-9 |