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Mutations in Caenorhabditis elegans actin, which are equivalent to human cardiomyopathy mutations, cause abnormal actin aggregation in nematode striated muscle

Actin is a central component of muscle contractile apparatuses, and a number of actin mutations cause diseases in skeletal, cardiac, and smooth muscles. However, many pathogenic actin mutations have not been characterized at cell biological and physiological levels. In this study, we tested whether...

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Detalles Bibliográficos
Autores principales: Hayashi, Yuriko, Ono, Kanako, Ono, Shoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446495/
https://www.ncbi.nlm.nih.gov/pubmed/30984387
http://dx.doi.org/10.12688/f1000research.18476.1