Design and Development of Novel 2-(Morpholinyl)-N-substituted Phenylquinazolin-4-amines as Selective COX-II Inhibitor

BACKGROUND: A novel series of 2-(Morpholin-4-yl)-N-phenylquinazolin-4-amine derivatives were synthesized and confirmed with spectral and elemental techniques. METHODS: The compounds were tested for analgesic and anti-inflammatory activity by various pain models in rodents whereas the selectivity tow...

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Detalles Bibliográficos
Autores principales: Dravyakar, Bhushan R., Khedekar, Pramod B., Khan, Tabassum, Sherje, Atul P., Patel, Kavit N., Suvarna, Vasanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446527/
https://www.ncbi.nlm.nih.gov/pubmed/30345927
http://dx.doi.org/10.2174/1871523017666181022144053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446527/
https://www.ncbi.nlm.nih.gov/pubmed/30345927
http://dx.doi.org/10.2174/1871523017666181022144053

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