Cargando…

Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula

Genomic imprinting is an epigenetic mechanism by which genes are expressed in a parental origin–dependent manner. We recently discovered that, like DNA methylation, oocyte-inherited H3K27me3 can also serve as an imprinting mark in mouse preimplantation embryos. In this study, we found H3K27me3 is st...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wenhao, Chen, Zhiyuan, Yin, Qiangzong, Zhang, Dan, Racowsky, Catherine, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446541/
https://www.ncbi.nlm.nih.gov/pubmed/30808660
http://dx.doi.org/10.1101/gad.323105.118