LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux

The activation of liver X receptor (LXR) promotes cholesterol efflux and repression of inflammatory genes with anti-atherogenic consequences. The mechanisms underlying the repressive activity of LXR are controversial and have been attributed to cholesterol efflux or to transrepression of activator p...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomas, David G., Doran, Amanda C., Fotakis, Panagiotis, Westerterp, Marit, Antonson, Per, Jiang, Hui, Jiang, Xian-Cheng, Gustafsson, Jan-Åke, Tabas, Ira, Tall, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446575/
https://www.ncbi.nlm.nih.gov/pubmed/30590048
http://dx.doi.org/10.1016/j.celrep.2018.11.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446575/
https://www.ncbi.nlm.nih.gov/pubmed/30590048
http://dx.doi.org/10.1016/j.celrep.2018.11.100

Ejemplares similares