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Widespread dynamic and pleiotropic expression of the melanocortin‐1‐receptor (MC1R) system is conserved across chick, mouse and human embryonic development

BACKGROUND: MC1R, a G‐protein coupled receptor with high affinity for alpha‐melanocyte stimulating hormone (αMSH), modulates pigment production in melanocytes from many species and is associated with human melanoma risk. MC1R mutations affecting human skin and hair color also have pleiotropic effect...

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Detalles Bibliográficos
Autores principales: Thomas, Anna C., Heux, Pauline, Santos, Chloe, Arulvasan, Wisenave, Solanky, Nita, Carey, Magalie E., Gerrelli, Dianne, Kinsler, Veronica A., Etchevers, Heather C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446732/
https://www.ncbi.nlm.nih.gov/pubmed/29316344
http://dx.doi.org/10.1002/bdr2.1183