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Widespread dynamic and pleiotropic expression of the melanocortin‐1‐receptor (MC1R) system is conserved across chick, mouse and human embryonic development
BACKGROUND: MC1R, a G‐protein coupled receptor with high affinity for alpha‐melanocyte stimulating hormone (αMSH), modulates pigment production in melanocytes from many species and is associated with human melanoma risk. MC1R mutations affecting human skin and hair color also have pleiotropic effect...
Autores principales: | Thomas, Anna C., Heux, Pauline, Santos, Chloe, Arulvasan, Wisenave, Solanky, Nita, Carey, Magalie E., Gerrelli, Dianne, Kinsler, Veronica A., Etchevers, Heather C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446732/ https://www.ncbi.nlm.nih.gov/pubmed/29316344 http://dx.doi.org/10.1002/bdr2.1183 |
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