Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress

Cells respond to stress in the ER by initiating the widely conserved unfolded protein response. Activation of the ER transmembrane nuclease IRE1 leads to the degradation of specific mRNAs, but how this pathway affects the ability of cells to recover from stress is not known. Here, we show that degra...

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Detalles Bibliográficos
Autores principales: Bae, Donghwi, Moore, Kristin A., Mella, Jessica M., Hayashi, Samantha Y., Hollien, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446841/
https://www.ncbi.nlm.nih.gov/pubmed/30787040
http://dx.doi.org/10.1083/jcb.201809027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446841/
https://www.ncbi.nlm.nih.gov/pubmed/30787040
http://dx.doi.org/10.1083/jcb.201809027

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