PLK1 plays dual roles in centralspindlin regulation during cytokinesis

Cytokinesis begins upon anaphase onset. An early step involves local activation of the small GTPase RhoA, which triggers assembly of an actomyosin-based contractile ring at the equatorial cortex. Here, we delineated the contributions of PLK1 and Aurora B to RhoA activation and cytokinesis initiation...

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Detalles Bibliográficos
Autores principales: Adriaans, Ingrid E., Basant, Angika, Ponsioen, Bas, Glotzer, Michael, Lens, Susanne M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446842/
https://www.ncbi.nlm.nih.gov/pubmed/30728176
http://dx.doi.org/10.1083/jcb.201805036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446842/
https://www.ncbi.nlm.nih.gov/pubmed/30728176
http://dx.doi.org/10.1083/jcb.201805036

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