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YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility

Cell migration initiates by traction generation through reciprocal actomyosin tension and focal adhesion reinforcement, but continued motility requires adaptive cytoskeletal remodeling and adhesion release. Here, we asked whether de novo gene expression contributes to this cytoskeletal feedback. We...

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Detalles Bibliográficos
Autores principales: Mason, Devon E., Collins, Joseph M., Dawahare, James H., Nguyen, Trung Dung, Lin, Yang, Voytik-Harbin, Sherry L., Zorlutuna, Pinar, Yoder, Mervin C., Boerckel, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446844/
https://www.ncbi.nlm.nih.gov/pubmed/30737263
http://dx.doi.org/10.1083/jcb.201806065