Cerebellar ataxia disease–associated Snx14 promotes lipid droplet growth at ER–droplet contacts

Lipid droplets (LDs) are nutrient reservoirs used by cells to maintain homeostasis. Nascent droplets form on the endoplasmic reticulum (ER) and grow following an influx of exogenous fatty acids (FAs). The budding of LDs requires extensive ER–LD crosstalk, but how this is regulated remains poorly und...

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Detalles Bibliográficos
Autores principales: Datta, Sanchari, Liu, Yang, Hariri, Hanaa, Bowerman, Jade, Henne, W. Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446855/
https://www.ncbi.nlm.nih.gov/pubmed/30765438
http://dx.doi.org/10.1083/jcb.201808133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446855/
https://www.ncbi.nlm.nih.gov/pubmed/30765438
http://dx.doi.org/10.1083/jcb.201808133

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