جاري التحميل…
Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing
In response to DNA damage, the transcription factor p53 accumulates in a series of pulses. While p53 dynamics play a critical role in regulating stress responses, how p53 pulsing affects target protein expression is not well understood. Recently, we showed that p53 pulses generate diversity in targe...
المؤلفون الرئيسيون: | , , |
---|---|
التنسيق: | Online مقال نص |
اللغة: | English |
منشور في: |
Rockefeller University Press
2019
|
الموضوعات: | |
الوصول للمادة أونلاين: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446860/ https://www.ncbi.nlm.nih.gov/pubmed/30745421 http://dx.doi.org/10.1083/jcb.201803063 |