جاري التحميل…

Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing

In response to DNA damage, the transcription factor p53 accumulates in a series of pulses. While p53 dynamics play a critical role in regulating stress responses, how p53 pulsing affects target protein expression is not well understood. Recently, we showed that p53 pulses generate diversity in targe...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hanson, Ryan L., Porter, Joshua R., Batchelor, Eric
التنسيق: Online مقال نص
اللغة:English
منشور في: Rockefeller University Press 2019
الموضوعات:
الوصول للمادة أونلاين:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446860/
https://www.ncbi.nlm.nih.gov/pubmed/30745421
http://dx.doi.org/10.1083/jcb.201803063