Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction

Microglia play a pivotal role in the coordination of brain development and have emerged as a critical determinant in the progression of neurodegenerative diseases; however, the role of microglia in the onset and progression of neurodevelopmental disorders is less clear. Here we show that conditional...

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Detalles Bibliográficos
Autores principales: Arnold, Thomas D., Lizama, Carlos O., Cautivo, Kelly M., Santander, Nicolas, Lin, Lucia, Qiu, Haiyan, Huang, Eric J., Liu, Chang, Mukouyama, Yoh-suke, Reichardt, Louis F., Zovein, Ann C., Sheppard, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446869/
https://www.ncbi.nlm.nih.gov/pubmed/30846482
http://dx.doi.org/10.1084/jem.20181290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446869/
https://www.ncbi.nlm.nih.gov/pubmed/30846482
http://dx.doi.org/10.1084/jem.20181290

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