Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke

Connexin43 (Cx43) function is influenced by kinases that phosphorylate specific serine sites located near its C-terminus. Stroke is a powerful inducer of kinase activity, but its effect on Cx43 is unknown. We investigated the impact of wild-type (WT) and knock-in Cx43 with serine to alanine mutation...

Descripción completa

Detalles Bibliográficos
Autores principales: Freitas-Andrade, Moises, Wang, Nan, Bechberger, John F., De Bock, Marijke, Lampe, Paul D., Leybaert, Luc, Naus, Christian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446879/
https://www.ncbi.nlm.nih.gov/pubmed/30872361
http://dx.doi.org/10.1084/jem.20171452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446879/
https://www.ncbi.nlm.nih.gov/pubmed/30872361
http://dx.doi.org/10.1084/jem.20171452

Ejemplares similares