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Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke

Connexin43 (Cx43) function is influenced by kinases that phosphorylate specific serine sites located near its C-terminus. Stroke is a powerful inducer of kinase activity, but its effect on Cx43 is unknown. We investigated the impact of wild-type (WT) and knock-in Cx43 with serine to alanine mutation...

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Detalles Bibliográficos
Autores principales:	Freitas-Andrade, Moises, Wang, Nan, Bechberger, John F., De Bock, Marijke, Lampe, Paul D., Leybaert, Luc, Naus, Christian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446879/ https://www.ncbi.nlm.nih.gov/pubmed/30872361 http://dx.doi.org/10.1084/jem.20171452

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