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Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes

Annexin A1 (ANXA1) is an endogenously produced anti-inflammatory protein, which plays an important role in the pathophysiology of diseases associated with chronic inflammation. We demonstrate that patients with type-2 diabetes have increased plasma levels of ANXA1 when compared to normoglycemic subj...

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Detalles Bibliográficos
Autores principales: Purvis, Gareth S. D., Collino, Massimo, Loiola, Rodrigo A., Baragetti, Andrea, Chiazza, Fausto, Brovelli, Martina, Sheikh, Madeeha H., Collotta, Debora, Cento, Alessia, Mastrocola, Raffaella, Aragno, Manuela, Cutrin, Juan C., Reutelingsperger, Chris, Grigore, Liliana, Catapano, Alberico L., Yaqoob, Magdi M., Norata, Giuseppe Danilo, Solito, Egle, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446914/
https://www.ncbi.nlm.nih.gov/pubmed/30972066
http://dx.doi.org/10.3389/fimmu.2019.00571