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Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies

Precision oncology trials for pediatric cancers require rapid and accurate detection of genetic alterations. Tumor variant identification should interrogate the distinctive driver genes and more frequent copy number variants and gene fusions that are characteristics of pediatric tumors. Here, we eva...

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Detalles Bibliográficos
Autores principales: Lorentzian, Amanda, Biegel, Jaclyn A, Ostrow, D Gigi, Rolf, Nina, Liu, Chi-Chao, Rassekh, S Rod, Deyell, Rebecca J, Triche, Timothy, Schultz, Kirk R, Rozmus, Jacob, Reid, Gregor S D, Lim, C James, Lange, Philipp F, Maxwell, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447067/
https://www.ncbi.nlm.nih.gov/pubmed/30976750
http://dx.doi.org/10.1093/jncics/pky079