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YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells

The properties and behaviour of stem cells rely heavily on signaling from the local microenvironment. At the apical end of Drosophila testis, self-renewal and differentiation of germline stem cells (GSCs) are tightly controlled by distinct somatic cells that comprise a specialised stem cell niche kn...

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Detalles Bibliográficos
Autores principales: Francis, Deepthy, Chanana, Bhavna, Fernandez, Beatriz, Gordon, Benjamin, Mak, Tiffany, Palacios, Isabel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447158/
https://www.ncbi.nlm.nih.gov/pubmed/30943201
http://dx.doi.org/10.1371/journal.pone.0213327