Transcription is a major driving force for plastid genome instability in Arabidopsis

Though it is an essential process, transcription can be a source of genomic instability. For instance, it may generate RNA:DNA hybrids as the nascent transcript hybridizes with the complementary DNA template. These hybrids, called R-loops, act as a major cause of replication fork stalling and DNA br...

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Detalles Bibliográficos
Autores principales: Pérez Di Giorgio, Juliana Andrea, Lepage, Étienne, Tremblay-Belzile, Samuel, Truche, Sébastien, Loubert-Hudon, Audrey, Brisson, Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447228/
https://www.ncbi.nlm.nih.gov/pubmed/30943245
http://dx.doi.org/10.1371/journal.pone.0214552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447228/
https://www.ncbi.nlm.nih.gov/pubmed/30943245
http://dx.doi.org/10.1371/journal.pone.0214552

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