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Cofilin-Mediated Actin Stress Response Is Maladaptive in Heat-Stressed Embryos

Environmental stress threatens the fidelity of embryonic morphogenesis. Heat, for example, is a teratogen. Yet how heat affects morphogenesis is poorly understood. Here, we identify a heat-inducible actin stress response (ASR) in Drosophila embryos that is mediated by the activation of the actin reg...

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Detalles Bibliográficos
Autores principales: Figard, Lauren, Zheng, Liuliu, Biel, Natalie, Xue, Zenghui, Seede, Hasan, Coleman, Seth, Golding, Ido, Sokac, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447309/
https://www.ncbi.nlm.nih.gov/pubmed/30917306
http://dx.doi.org/10.1016/j.celrep.2019.02.092