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Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr (-/-) mice

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, particularly in obese and type 2 diabetic individuals. NAFLD ranges in severity from benign steatosis to nonalcoholic steatohepatitis (NASH); and NASH can progress to cirrhosis, primary hepatocel...

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Detalles Bibliográficos
Autores principales: Garcia-Jaramillo, Manuel, Spooner, Melinda H., Löhr, Christiane V., Wong, Carmen P., Zhang, Weijian, Jump, Donald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447358/
https://www.ncbi.nlm.nih.gov/pubmed/30943218
http://dx.doi.org/10.1371/journal.pone.0214387