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Near-infrared upconversion–activated CRISPR-Cas9 system: A remote-controlled gene editing platform

As an RNA-guided nuclease, CRISPR-Cas9 offers facile and promising solutions to mediate genome modification with respect to versatility and high precision. However, spatiotemporal manipulation of CRISPR-Cas9 delivery remains a daunting challenge for robust effectuation of gene editing both in vitro...

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Detalles Bibliográficos
Autores principales: Pan, Yongchun, Yang, Jingjing, Luan, Xiaowei, Liu, Xinli, Li, Xueqing, Yang, Jian, Huang, Ting, Sun, Lu, Wang, Yuzhen, Lin, Youhui, Song, Yujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447385/
https://www.ncbi.nlm.nih.gov/pubmed/30949579
http://dx.doi.org/10.1126/sciadv.aav7199