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SPECIFICATION OF POSITIONAL IDENTITY IN FOREBRAIN ORGANOIDS

Human brain organoids generated with current technologies recapitulate histological features of the human brain, but they lack a reproducible topographic organization. During development, spatial topography is determined by gradients of signaling molecules released from discrete signaling centers. W...

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Detalles Bibliográficos
Autores principales: Cederquist, Gustav Y., Asciolla, James J., Tchieu, Jason, Walsh, Ryan M, Cornacchia, Daniela, Resh, Marilyn D., Studer, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447454/
https://www.ncbi.nlm.nih.gov/pubmed/30936566
http://dx.doi.org/10.1038/s41587-019-0085-3