NKG2A is a NK cell exhaustion checkpoint for HCV persistence

Exhaustion of cytotoxic effector natural killer (NK) and CD8(+) T cells have important functions in the establishment of persistent viral infections, but how exhaustion is induced during chronic hepatitis C virus (HCV) infection remains poorly defined. Here we show, using the humanized C/O(Tg) mice...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wang, Xiao-mei, Li, Shu-ran, Twelkmeyer, Trix, Wang, Wei-hong, Zhang, Sheng-yuan, Wang, Shu-feng, Chen, Ji-zheng, Jin, Xia, Wu, Yu-zhang, Chen, Xin-wen, Wang, Sheng-dian, Niu, Jun-qi, Chen, Hai-rong, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447531/
https://www.ncbi.nlm.nih.gov/pubmed/30944315
http://dx.doi.org/10.1038/s41467-019-09212-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447531/
https://www.ncbi.nlm.nih.gov/pubmed/30944315
http://dx.doi.org/10.1038/s41467-019-09212-y

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