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Aescin-Cholesterol Complexes in DMPC Model Membranes: A DSC and Temperature-Dependent Scattering Study

The saponin aescin, a mixture of triterpenoid saponins, is obtained from the seeds of the horse chestnut tree Aesculus hippocastanum. The β-form employed in this study is haemolytically active. The haemolytic activity results from the ability of aescin to form strong complexes with cholesterol in th...

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Detalles Bibliográficos
Autores principales: Sreij, Ramsia, Dargel, Carina, Schweins, Ralf, Prévost, Sylvain, Dattani, Rajeev, Hellweg, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447539/
https://www.ncbi.nlm.nih.gov/pubmed/30944386
http://dx.doi.org/10.1038/s41598-019-41865-z