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Inhibition of miR-155 reduces impaired autophagy and improves prognosis in an experimental pancreatitis mouse model

Acute pancreatitis (AP) is a common digestive disease characterized by inflammation of the pancreas. MiR-155 plays a role in promoting inflammation and inhibiting the activation of anti-inflammatory pathways. Impaired autophagy could promote zymogen activation, abnormal acinar cell secretion, cell d...

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Detalles Bibliográficos
Autores principales: Wan, Jianhua, Yang, Xiaoyu, Ren, Yuping, Li, Xueyang, Zhu, Yin, Haddock, Ashley N, Ji, Baoan, Xia, Liang, Lu, Nonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447551/
https://www.ncbi.nlm.nih.gov/pubmed/30944299
http://dx.doi.org/10.1038/s41419-019-1545-x