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Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting

Whole genome sequencing (WGS) can elucidate Mycobacterium tuberculosis (Mtb) transmission patterns but more data is needed to guide its use in high-burden settings. In a household-based TB transmissibility study in Peru, we identified a large MIRU-VNTR Mtb cluster (148 isolates) with a range of resi...

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Detalles Bibliográficos
Autores principales: Dixit, Avika, Freschi, Luca, Vargas, Roger, Calderon, Roger, Sacchettini, James, Drobniewski, Francis, Galea, Jerome T., Contreras, Carmen, Yataco, Rosa, Zhang, Zibiao, Lecca, Leonid, Kolokotronis, Sergios-Orestis, Mathema, Barun, Farhat, Maha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447560/
https://www.ncbi.nlm.nih.gov/pubmed/30944370
http://dx.doi.org/10.1038/s41598-019-41967-8