Cargando…

Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome

The NLRP3 inflammasome promotes the pathogenesis of metabolic, neurodegenerative and infectious diseases. Increasing evidences show that the NLRP3 inflammasome is a promising therapeutic target in inflammatory diseases. Glucosamine is widely used as a dietary supplement to promote the health of cart...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiu, Hsiao-Wen, Li, Lan-Hui, Hsieh, Chih-Yu, Rao, Yerra Koteswara, Chen, Fang-Hsin, Chen, Ann, Ka, Shuk-Man, Hua, Kuo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447579/
https://www.ncbi.nlm.nih.gov/pubmed/30944389
http://dx.doi.org/10.1038/s41598-019-42130-z