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Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome
The NLRP3 inflammasome promotes the pathogenesis of metabolic, neurodegenerative and infectious diseases. Increasing evidences show that the NLRP3 inflammasome is a promising therapeutic target in inflammatory diseases. Glucosamine is widely used as a dietary supplement to promote the health of cart...
Autores principales: | Chiu, Hsiao-Wen, Li, Lan-Hui, Hsieh, Chih-Yu, Rao, Yerra Koteswara, Chen, Fang-Hsin, Chen, Ann, Ka, Shuk-Man, Hua, Kuo-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447579/ https://www.ncbi.nlm.nih.gov/pubmed/30944389 http://dx.doi.org/10.1038/s41598-019-42130-z |
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