Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions

The pharmacokinetic profile of a drug can be different when delivered as a nanosuspension compared with a true solution, which may in turn affect the therapeutic effect of the drug. The goal of this study was to prepare itraconazole nanosuspensions (ITZ-Nanos) stabilized by an amphipathic polymer, p...

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Detalles Bibliográficos
Autores principales: Yuan, Qi, Wang, Yanling, Song, Rufeng, Hou, Xianqiao, Yu, Keke, Zheng, Jiaojiao, Zhang, Juanmei, Pu, Xiaohui, Han, Jihong, Zong, Lanlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447661/
https://www.ncbi.nlm.nih.gov/pubmed/30983994
http://dx.doi.org/10.3389/fphar.2019.00225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447661/
https://www.ncbi.nlm.nih.gov/pubmed/30983994
http://dx.doi.org/10.3389/fphar.2019.00225

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