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Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions

The pharmacokinetic profile of a drug can be different when delivered as a nanosuspension compared with a true solution, which may in turn affect the therapeutic effect of the drug. The goal of this study was to prepare itraconazole nanosuspensions (ITZ-Nanos) stabilized by an amphipathic polymer, p...

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Detalles Bibliográficos
Autores principales:	Yuan, Qi, Wang, Yanling, Song, Rufeng, Hou, Xianqiao, Yu, Keke, Zheng, Jiaojiao, Zhang, Juanmei, Pu, Xiaohui, Han, Jihong, Zong, Lanlan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447661/ https://www.ncbi.nlm.nih.gov/pubmed/30983994 http://dx.doi.org/10.3389/fphar.2019.00225

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