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Mitochondrial DNA Leakage Caused by Streptococcus pneumoniae Hydrogen Peroxide Promotes Type I IFN Expression in Lung Cells

Streptococcus pneumoniae (S. pn), the bacterial pathogen responsible for invasive pneumococcal diseases, is capable of producing substantial amounts of hydrogen peroxide. However, the impact of S. pn-secreted hydrogen peroxide (H(2)O(2)) on the host immune processes is not completely understood. Her...

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Detalles Bibliográficos
Autores principales: Gao, Yue, Xu, Wenchun, Dou, Xiaoyun, Wang, Hong, Zhang, Xuemei, Yang, Shenghui, Liao, Hongyi, Hu, Xuexue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447684/
https://www.ncbi.nlm.nih.gov/pubmed/30984149
http://dx.doi.org/10.3389/fmicb.2019.00630