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N,N-Dimethylaminoxy Carbonyl, a Polar Protecting Group for Efficient Peptide Synthesis

Peptide coupling with minimal protection is one of the desired methods for the synthesis of peptides and proteins. To achieve regioselective amide bond formation, side chain protection is often essential; however, protecting groups potentially diminish peptide solubility and render the polar polyami...

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Detalles Bibliográficos
Autores principales: Okamoto, Ryo, Ono, Emiko, Izumi, Masayuki, Kajihara, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447706/
https://www.ncbi.nlm.nih.gov/pubmed/30984743
http://dx.doi.org/10.3389/fchem.2019.00173