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The Antiviral Apparatus: STING and Oncolytic Virus Restriction

A network of pattern recognition receptors (PRRs) is responsible for the detection of invading viruses and acts as the trigger for the host antiviral response. Central to this apparatus is stimulator of interferon genes (STING), which functions as a node and integrator of detection signals. Owing to...

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Detalles Bibliográficos
Autores principales: Lee, Joel, Ghonime, Mohammed G., Wang, Ruoning, Cassady, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447737/
https://www.ncbi.nlm.nih.gov/pubmed/30989105
http://dx.doi.org/10.1016/j.omto.2019.02.002