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Glucose starvation induces resistance to metformin through the elevation of mitochondrial multidrug resistance protein 1

Metformin, a drug for type 2 diabetes mellitus, has shown therapeutic effects for various cancers. However, it had no beneficial effects on the survival rate of human malignant mesothelioma (HMM) patients. The present study was performed to elucidate the underlying mechanism of metformin resistance...

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Detalles Bibliográficos
Autores principales: Hwang, Sung‐Hyun, Kim, Myung‐Chul, Ji, Sumin, Yang, Yeseul, Jeong, Yeji, Kim, Yongbaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447852/
https://www.ncbi.nlm.nih.gov/pubmed/30689265
http://dx.doi.org/10.1111/cas.13952