Novel Group of Imidazole Derivatives as Atypical Selective Cyclooxygenase-2 Inhibitors: Design, Synthesis and Biological Evaluation

In this study, a new series of 5-substituted 1-benzyl-2-(methylsulfonyl)-1-H-imidazole with atypical structure-activity relationship was designed, synthesized, and biological evaluated as selective cyclooxygenase-2 inhibitors. Docking studies revealed that although the pharmacophoric substitute of t...

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Detalles Bibliográficos
Autores principales: Kiani, Azin, Rezaee, Elham, Tabatabai, Sayyed Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447865/
https://www.ncbi.nlm.nih.gov/pubmed/31011344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447865/
https://www.ncbi.nlm.nih.gov/pubmed/31011344

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