Design, Synthesis, Molecular Modeling, In Silico ADME Studies and Anti-HIV-1 Assay of New Diazocoumarin Derivatives

Some new diazo incorporated coumarin compounds were designed and synthesized to evaluate their anti-HIV activity. Overall, compounds were active against HIV at 100 μM. Additionally, no cytotoxic effect was observed at this concentration. The compound with 4-chlorobenzyl group indicated the best anti...

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Detalles Bibliográficos
Autores principales: Alimi Livani, Zeynab, Safakish, Mahdieh, Hajimahdi, Zahra, Soleymani, Sepehr, Zabihollahi, Rezvan, Aghasadeghi, Mohammad Reza, Alipour, Eskandanr, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447871/
https://www.ncbi.nlm.nih.gov/pubmed/31011343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447871/
https://www.ncbi.nlm.nih.gov/pubmed/31011343

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