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BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway

The novel bromophenol derivative, 3-(3-bromo-5-methoxy-4-(3-(piperidin-1-yl)propoxy)benzylidene)-N-(4-bromophenyl)-2-oxoindoline-5-sulfonamide (BOS-93), was synthesized in the CAS Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences (Qingdao, China). Ex...

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Detalles Bibliográficos
Autores principales: Guo, Chuanlong, Wang, Lijun, Zhao, Yue, Jiang, Bo, Luo, Jiao, Shi, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447907/
https://www.ncbi.nlm.nih.gov/pubmed/30988770
http://dx.doi.org/10.3892/etm.2019.7402